eBook Description

Antibiotic Drug Resistance, 1st Edition (ISBN-13: 9781119282525) offers a thorough and authoritative exploration of antibiotic science, focusing on the mechanisms of drug resistance and the development of strategies to prevent and treat infectious diseases. This book serves as a critical resource for researchers, clinicians, and policymakers who are involved in the battle against antibiotic resistance.

:

• Comprehensive
  

  Overview

  : Covers the broad field of antibiotic drug resistance, from the underlying mechanisms to the socioeconomic impacts and public policy implications.

• Practical Guidance: Provides actionable insights for translating research into tools for prevention, diagnosis, and treatment.
• Interdisciplinary Approach: Links strategies for analyzing microbes to the development of new drugs and discusses the impact of antibiotic resistance on public health and policy.

ISBN Information:

• Print ISBN-13: 9781119282525
• eText ISBN-13: 9781119282556

:

Part I: Current Antibiotics and Their Mechanism of Action

• Resistance to Aminoglycosides
• Mechanisms of Action and of Resistance to Quinolones
• Beta-Lactams
• Glycopeptide Antibiotics
• Current Macrolide Antibiotics and Their Mechanisms of Action

Part II: Mechanism of Antibiotic Resistance 6. Impact of Key and Secondary Drug Resistance Mutations on Structure and Activity of β-Lactamases
7. Acquired Resistance from Gene Transfer
8. Antimicrobial Efflux Pumps
9. Bacterial Persistence in Biofilms and Antibiotics

Part III: Socio-Economic Perspectives and Impact of AR 10. Sources of Antibiotic Resistance
11. Antibiotic Resistance as a Worldwide Health Problem
12. Extended-Spectrum-β-Lactamase and Carbapenemase-Producing Enterobacteriaceae in Food-Producing Animals in Europe

Part IV: Therapeutic Strategies for Overcoming AR 13. AR Mechanism-Based Drug Design
14. Antibiotics from Natural Sources
15. Bacteriophage Proteins as Antimicrobials to Combat Antibiotic Resistance
16. Antibiotic Modification Addressing Resistance
17. Sensitizing Agents to Restore Antibiotic Resistance
18. Repurposing Antibiotics to Treat Resistant Gram-Negative Pathogens
19. Nontraditional Medicines for Treatment of Antibiotic Resistance
20. Therapeutic Options for Treatment of Infections by Pathogenic Biofilms

Part V: Strategies to Prevent the Spread of AR 21. Rapid Analytical Methods to Identify Antibiotic-Resistant Bacteria
22. Effective Methods for Disinfection and Sterilization
23. Strategies to Prevent the Spread of Antibiotic Resistance

Part VI: Public Policy 24. Strategies to Reduce or Eliminate Resistant Pathogens in the Environment

Index

Antibiotic Drug Resistance, 1st Edition is an essential guide for anyone involved in the fight against antibiotic resistance. Whether you’re a researcher, healthcare professional, or policymaker, this book equips you with the knowledge and tools to address one of the most significant challenges in modern medicine.